Group C: Sporting Lisbon, Borussia Dortmund, Ajax, Besiktas
Group D: Inter Milan, Real Madrid, Shakhtar Donetsk, Sheriff Tiraspol
Group E: Bayern Munich, Barcelona, Benfica, Dynamo Kyiv
Group F: Villarreal, Manchester United, Atalanta, Young Boys
Group G: Lille, Sevilla, FC Salzburg, Wolfsburg
Group H: Chelsea, Juventus, Zenit St Petersburg, Malmo
Matchday 1: 14/15 September 2021
Matchday 2: 28/29 September 2021
Matchday 3: 19/20 Oktober 2021